9. Διακρίσεις Εργαστηρίου

1. Υποψηφιότητα για Πρόσωπα της Χρονιάς 2021

 

Researchers at the University of Patras change Laplace's law

Recently, in the January issue of the journal Physics of Fluids, published by the American Institute of Physics, appeared a research paper that changes Laplace's law.

More specifically, by incorporating Laplace's law into a newly-generalized and analytical mathematical expression, it is possible for the first time to accurately calculate the wall stress on a curved tube containing a moving liquid.

The generalization of Laplace's law arose as a result of fluid mechanics attempt to interpret the aortic size paradox (ASP) in the ascending part of the thoracic aorta (ATA).

ASP is defined as the phenomenon in which, in clinical practice, there are multiple cases of rupture of the ATA aneurysm with a diameter < 5.5 cm and which until now could not be interpreted by Laplace's law. This work, with the generalization of Laplace's law, interprets this medical paradox.

This interpretation is potentially of great clinical importance because, with appropriate treatment (in less than 5.5 cm aneurysms in the general population), the fatal complication of rupture of the ATA aneurysm can be prevented in the future.

The formulation of a new generalized expression, through a new mathematical theory, for the prediction of the rupture of an ATA aneurysm, is the result of a collaboration between Physicists, Medical Radiation Physicists specializing in vascular fluid mechanics, and a Radiologist with experience in large blood vessels imaging pathology.

The team of researchers was led by the Emeritus Professor of Fluid Mechanics of the Department of Physics of the University of Patras George Karahalios. The team also included the researchers: Marina Karachaliou, Gerasimos Messaris MP, Vassilios Loukopoulos, Konstantinos Koutsojannis MP and Petros Zampakis.


 

ARTICLE TITLE

The missing role of hydrodynamic stresses on ascending aortic dissection

[Phys. Fluids 33, 011901 (2021); https://doi.org/10.1063/5.0029346]       

AUTHORS

Marina Karachaliou,1 Gerasimos Messaris,2 Vassilios Loukopoulos,1 Constantinos Koutsojannis,3 Petros Zampakis,4 and George Karahalios1

AUTHOR AFFILIATIONS

1 Department of Physics, University of Patras, Greece

2 Department of Medical Physics, University Hospital of Patras, Greece

3 Department of Health Physics and Computational Intelligence, School of Health Rehabilitation Sciences, University of Patras, Greece

4 Department of Radiology, University Hospital of Patras, Greece

 

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